15 January 2012

Treatment and Prognosis of IgA Nephropathy

IgA nephropathy is a common name of several immune kidney disease the same disease. It is a kind of primary glomerulopathy, and the types of IgA nephropathy are different. Therefore, due to different symptoms and the disease, the prognosis of IgA nephropathy of different types are different.
In general, we can divide IgA nephropathy into four types according to symptoms.
Type I Simple hematuria or (and) a mild proteinuria
As for what kind of patients, special treatment is not required in the general population. Patients should avoid overexertion, cold and prevent infections, and never use a drug nephrotoxicity. If patients have recurrent infections of the tonsils, it is suggested they have an operation to remove it. And make sure that patients are made after the infection was controlled in a state of stable disease. This type of IgA nephropathy is generally a good prognosis, and renal function in these patients can expect to keep a normal level for a long time.
Type II of massive proteinuria (> 3.5g/dl) or nephrotic syndrome
Patients with mild symptoms and those who still retain normal renal function, the application of glucocorticoids could be used as a way to relieve symptoms and maintain normal renal function. However, it is not advisable to depend on glucocorticoids for a long time, for his kind of side effects such as obesity, osteoporosis, and immunity declines, etc. For those with damaged renal function and obvious symptoms, it is recommended that patients receive osmotherapy Micro-Chinese Medicine, which is able to effectively control the development of the disease, without side effects. As for patients with severe symptoms, they should take stem cell transplant in time to restore renal function remained. Or the development of the disease can not be controlled in time, it will pass with chronic renal failure. Therefore, due to poor prognosis of this type, patients should receive aggressive treatment.
Type III progressive glomerulonephritis
Patients with this type of IgA nephropathy, clinic, generally have increased IgA complex when examined by renal biopsy. Acute renal failure is a frequent clinical manifestation in these patients. When necessary, patients should receive intensive treatment, such as methylprednisolone pulse therapy and cyclophosphamide pulse therapy, etc. and integration of stem cell and Micro-Chinese medicine are accessible way block the development of the disease to end stage renal disease, to reverse the poor prognosis.
Type VI of chronic glomerulonephritis
The treatment of this type of IgA nephropathy should be focused on averting the deterioration of kidney function. For those patients with hypertension accompanied by control of hypertension is also crucial. Patients with albuminuria> 1g/dl and normal renal function can be treated with an ACEI and ARA, for patients with albuminuria> 2g/dl and mild renal dysfunction, osmotherapy Micro-Chinese Medicine can be trusted to block deterioration; If the index is exceeded creatinine 265╬╝mol / L (3mg/d1), it is suggested that the stem cell transplantation, or patients will gradually depend on dialysis.
From the introduction above, we can see that the prognosis of IgA nephropathy differs from the disease status and extent of symptoms. And suggestions for treatment are for the general case, the treatment of the concrete must follow the orders of doctors. Any questions, please contact the consultant on-line.